Current Status of Computer-Aided Drug Design for Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Current Status of Computer-Aided Drug Design for Type 2 Diabetes
BACKGROUND Diabetes is a metabolic disorder that requires multiple therapeutic approaches. The pancreas loses its functionality to properly produce the insulin hormone in patients with diabetes mellitus. In 2012, more than one million people worldwide died as a result of diabetes, which was the eighth leading cause of death. OBJECTIVE Most drugs currently available and approved by the U.S. Fo...
متن کاملClassifications and Properties of Materials for Chairside Computer-Aided Design/Computer-Aided Manufacturing Dentistry: A Review
Background and Aim: Chairside computer-aided design/computer-aided manufacturing (CAD/CAM) systems have become considerably more accurate, reliable, efficient, fast, and prevalent since 1985 when CEREC was introduced. The inceptive restorative material option for chairside CAD/CAM restorations was limited to ceramic blocks. Today, restorative material options have been multiplied and include me...
متن کاملAn Overview of Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) in Restorative Dentistry
Objective: To review the current knowledge of CAD/CAM in dentistry and its development in the mentioned field. Sources: An electronic search was conducted across Ovid Medline, complemented by manual search across individual databases, such as Cochrane, Medline and ISI Web of Science databases and Google Scholar for literature analysis on the mentioned topic. The studies were reviewed thoroughly...
متن کاملActive Search for Computer-aided Drug Design.
We consider lead discovery as active search in a space of labelled graphs. In particular, we extend our recent data-driven adaptive Markov chain approach, and evaluate it on a focused drug design problem, where we search for an antagonist of an αv integrin, the target protein that belongs to a group of Arg-Gly-Asp integrin receptors. This group of integrin receptors is thought to play a key rol...
متن کاملcomputer aided forging design
in forging design the significant parameters are maximum load or energy which are required for the selection of forging press or hammer. these two parameters are varied by the other paramelers such as the geometry of die cavity, flash dimensions, shape of the work piece, friction, mechanical properties of the metal to be forged, temperature, strain rate, and number of the forging operation. the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Computer Aided-Drug Design
سال: 2016
ISSN: 1573-4099
DOI: 10.2174/1573409912666160426120709